Advances in Engineering Innovation

Advances in Engineering Innovation

Vol. 5, 22 December 2023


Open Access | Article

Underlying factors that may affect the treatment of Platelet-rich plasma in chronic wounds

Zhiqin Dong * 1 , Jijin Wu 2
1 The First Affiliated Hospital of Jinan University
2 Jinan University

* Author to whom correspondence should be addressed.

Advances in Engineering Innovation, Vol. 5 Advances in Engineering Innovation,
Published 22 December 2023. © 2023 The Author(s). Published by EWA Publishing
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Citation Zhiqin Dong, Jijin Wu. Underlying factors that may affect the treatment of Platelet-rich plasma in chronic wounds. AEI (2023) Vol. 5: 0-0. DOI: 10.54254/2977-3903/5/2023055.

Abstract

Platelet-rich plasma (PRP) has gained widespread usage in the treatment of various chronic wounds due to its ease of preparation and high safety profile. But not every treatment can achieve satisfactory results. The quality of PRP is based on individual biological characteristics. Autologous PRP technology is greatly affected by the patient himself. Individual responses to PRP treatment are different and will produce different therapeutic effects. Especially in patients with uncontrollable factors such as aging, diabetes, and coronary heart disease, the use of antiplatelet drugs may potentially reduce the quality of autologous platelet-rich plasma (PRP). When treating related diseases, it is important to consider the impact of factors such as age, gender, and the specific disease. Currently, many researchers are focusing on the development of allogeneic PRP technology to avoid the inconvenience of collecting autologous blood and reduce potential negative effects that may exist in the patient's disease itself. In this review, we explore the factors generally recognized in current research which influence the efficacy of PRP.

Keywords

platelet-rich plasma, chronic wounds, autologous, allogeneic

References

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Data Availability

The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.

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Volume Title
ISBN (Print)
ISBN (Online)
Published Date
22 December 2023
Series
Advances in Engineering Innovation
ISSN (Print)
2977-3903
ISSN (Online)
2977-3911
DOI
10.54254/2977-3903/5/2023055
Copyright
© 2023 The Author(s)
Open Access
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

Copyright © 2023 EWA Publishing. Unless Otherwise Stated